Josh Denny is a Professor of Biomedical Informatics and Medicine, Director of the Center for Precision Medicine, and Vice President for Personalized Medicine. His research interests include natural language processing, accurate phenotype identification from electronic medical record data, and using the electronic medical record to discover genome‐phenome associations to better understand disease and drug response, including the development of the EMR‐based phenome‐wide association (PheWAS).

He is PI of the Data and Research Center of the All of Us Research Program (previously called the Precision Medicine Initiative Cohort Program), which will eventually enroll at least 1 million Americans in an effort to understand the genetic, environmental, and behavioral factors that influence human health and disease. He is also PI for Vanderbilt sites in the Electronic Medical Records and Genomics (eMERGE) Network, Pharmacogenomics Research Network (PGRN), and the Implementing Genomics Into Practice (IGNITE) Network.

He is a member of the National Academy of Medicine, the American Society for Clinical Investigation, and the American College of Medical Informatics. He remains active in teaching medical students and clinical roles.